Codeine may enhance the neuromuscular blocking motion of skeletal muscle relaxants and produce an elevated degree of respiratory melancholy.
Carcinogenicity, mutagenicity, and fertility reports haven't been done with Promethazine with Codeine Oral Remedy; even so, printed data is obtainable for the individual Energetic substances.
Promethazine hydrochloride was not mutagenic during the in vitro bacterial reverse mutation assay or clastogenic while in the in vitro Chinese hamster ovary (CHO) cell chromosomal aberration assay.
question your health practitioner concerning the Safe and sound usage of Alcoholic beverages when you are getting this medication. Alcohol may make the Unwanted side effects of promethazine even worse.
If somebody has overdosed and it has significant signs or symptoms like passing out or problems respiration, contact 911. Or else, phone a poison Handle Middle at once.
Monitoring the patient for indications and/or indications of respiratory melancholy, cardiac arrhythmias, and narcotic bowel syndrome
The phosphate salt of codeine takes place as white, needle-formed crystals or white crystalline powder. Codeine phosphate is freely soluble in water and marginally soluble in alcohol. The molecular weight is 406.37. Its molecular components is C18H21NO3•H3PO4 • ½ H2O, and it's got the next chemical composition.
Consider this medicine only as directed by your medical professional. Usually do not just take extra of it, will not just take it much more usually, and don't get it for an extended time than your health care provider ordered.
When you are giving promethazine to a child, view the child to be sure she or he would not get hurt when Driving a bike or participating in other actions that would be hazardous.
Small children Postmarketing situations of respiratory depression, together with fatalities, happen to be noted with use of promethazine in pediatric clients. Concomitant administration with other respiratory depressants might raise the risk of respiratory melancholy.
People today using any opioid medication Have a very threat of overdose if they do not stick to the prescribed dosage. Indications of overdose contain:
Ailments OF USE: The information Within this databases is meant to complement, not substitute for, the know-how and judgment of healthcare specialists. The information isn't meant to cover all feasible employs, directions, safety measures, drug interactions or adverse effects, nor really should or not it's construed to point that use of a selected drug is Secure, suitable or effective for you personally or everyone else.
For anyone who is having promethazine liquid, don't make use of a household spoon to measure your dose. Use the measuring spoon or cup that arrived Using the medication or use a spoon manufactured specifically for measuring medication.
Hepatic impairment: According to manufacturer labeling, no studies are actually done on patients with hepatic impairment. That's why clinicians ought Promethazine codeine syrup to prescribe codeine in a decreased dose in these sufferers.